Applications

FA

Synonyms:

Filimirasin, Filmirisin

Formulation:

Crystalline solid

Chemical Name:

(17E,19E,21E,23E,25E)-4,6,8,10,12,14,16,27-octahydroxy-3-(1-hydroxyhexyl)-17,28-dimethyl-1-oxacyclooctacosa-17,19,21,23,25-pentaen-2-one

Molecular Formula:

C₃₅H₅₈O₁₁

Molecular Weight:

654.8

CAS Number

480-49-9

Purity:

≥85%

Storage Conditions:

Product should be kept at -20°C.

References:

Bittman, R., & Fischkoff, S. A. (1972). Fluorescence studies of the binding of the polyene antibiotics filipin III, amphotericin B, nystatin, and lagosin to cholesterol.Proceedings of the National Academy of Sciences,69(12), 3795-3799.

Pandey, R. G., & RINEHART, K. L. (1970). POLYENE ANTIBIOTICS. V. CHARACTERIZATION OF COMPONENTS OF THE FILIPIN COMPLEX BY MASS SPECTROMETRY 1).The Journal of antibiotics,23(8), 414-417.

Orlandi, P. A., & Fishman, P. H. (1998). Filipin-dependent inhibition of cholera toxin: evidence for toxin internalization and activation through caveolae-like domains.The Journal of cell biology,141(4), 905-915.