Applications

FA

Synonyms:

NS398, NS 398

Formulation:

Crystalline solid

Chemical Name:

N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide

Molecular Formula:

C₁₃H₁₈N₂O₅S

Molecular Weight:

314.4

CAS Number

123653-11-2

Purity:

≥98%

Storage Conditions:

Product should be kept at room temperature.

References:

Futaki, N., Yoshikawa, K., Hamasaka, Y., Arai, I., Higuchi, S., Iizuka, H., & Otomo, S. (1993). NS-398, a novel non-steroidal anti-inflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions.General Pharmacology: The Vascular System,24(1), 105-110.

Futaki, N., Takahashi, S., Yokoyama, M., Arai, I., Higuchi, S., & Otomo, S. (1994). NS-398, a new anti-inflammatory agent, selectively inhibits prostaglandin G/H synthase/cyclooxygenase (COX-2) activity in vitro.Prostaglandins,47(1), 55-59.

Joki, T., Heese, O., Nikas, D. C., Bello, L., Zhang, J., Kraeft, S. K., ... & Black, P. M. (2000). Expression of cyclooxygenase 2 (COX-2) in human glioma and in vitro inhibition by a specific COX-2 inhibitor, NS-398.Cancer research,60(17), 4926-4931.