Applications

FA

Synonyms:

PMA, TPA, Phorbol ester, croton oil.

Formulation:

Crystalline solid

Chemical Name:

12-O-Tetradecanoylphorbol-13-acetate

Molecular Formula:

C₃₆H₅₆O₈

Molecular Weight:

616.8

CAS Number

16561-29-8

Purity:

≥98%

Storage Conditions:

Product should be kept at -20°C.

References:

Emerit, I., & Cerutti, P. A. (1981). Tumour promoter phorbol-12-myristate-13-acetate induces chromosomal damage via indirect action.

Holtmann, H. E. L. M. U. T., & Wallach, D. A. V. I. D. (1987). Down regulation of the receptors for tumor necrosis factor by interleukin 1 and 4 beta-phorbol-12-myristate-13-acetate.The Journal of Immunology,139(4), 1161-1167.

Thompson, C. B., Lindsten, T., Ledbetter, J. A., Kunkel, S. L., Young, H. A., Emerson, S. G., ... & June, C. H. (1989). CD28 activation pathway regulates the production of multiple T-cell-derived lymphokines/cytokines.Proceedings of the National Academy of Sciences,86(4), 1333-1337.