Applications

FA

Synonyms:

AGN-191183, Arotinoid acid, Arotinoic acid, Ro 13-7410

Formulation:

Crystalline solid

Chemical Name:

4-[(E)-2-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)prop-1-enyl]benzoic acid

Molecular Formula:

C₂₄H₂₈O₂

Molecular Weight:

348.5

CAS Number

71441-28-6

Purity:

≥98%

Storage Conditions:

Product should be kept at -20°C.

References:

Pignatello, M. A., Kauffman, F. C., & Levin, A. A. (1997). Multiple factors contribute to the toxicity of the aromatic retinoid, TTNPB (Ro 13-7410): binding affinities and disposition.Toxicology and applied pharmacology,142(2), 319-327.

Åström, A., Pettersson, U., Krust, A., Chambon, P., & Voorhees, J. J. (1990). Retinoic acid and synthetic analogs differentially activate retinoic acid receptor dependent transcription.Biochemical and biophysical research communications,173(1), 339-345.

Hossain, M. Z., & Bertram, J. S. (1994). Retinoids suppress proliferation, induce cell spreading, and up-regulate connexin43 expression only in postconfluent 10T1/2 cells: implications for the role of gap junctional communication.Cell growth & differentiation: the molecular biology journal of the American Association for Cancer Research,5(11), 1253-1261.