Anti-Human CD20 Purified
货号:02311-20-100
规格:100 ug
价格:1210
产品类型:流式抗体
品牌:PeproTech
物种:人
宿主:小鼠
抗体亚型:IgG
荧光染料:Purified
Description
The 2H7 monoclonal antibody specifically reacts with human CD20, a 33-37kDA B-lymphocyte surface molecule. CD20 is an unglycosylated four-transmembrane phosphoprotein expressed by B cells in all stage of development, except the final plasma cells. It has been reported that the molecule is involved in B cell activation and has also been observed on a subset of circulating T lymphocytes.
Additional Information
Clone | 2H7 |
Format: | Purified |
Applications | FC, IHC |
Reactivity | Human |
Isotype: | Mouse IgG2b, kappa |
Research Interest: | Adaptive Immunity |
Cell Type: | B Cells |
Preperation: | The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. |
Formulation: | Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2. |
References: | Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989. Polyak, M. J., & Deans, J. P. (2002). Alanine-170 and proline-172 are critical determinants for extracellular CD20 epitopes; heterogeneity in the fine specificity of CD20 monoclonal antibodies is defined by additional requirements imposed by both amino acid sequence and quaternary structure.Blood,99(9), 3256-3262. Schlossman, S. F. (1995).Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press. |