Recombinant Human TNF-β
货号：300-01B-100,300-01B-1000,300-01B-20,300-01B-250,300-01B-5,300-01B-50,300-01B-500
规格：100ug,1mg,20ug,250ug,5ug,50ug,500ug
价格：6379,25574,1418,11161,582,3831,16588
产品类型：细胞因子添加物
品牌：PeproTech
| 产品描述:TNF-β is a potent mediator of inflammatory and immune responses. It belongs to the TNF family of ligands, and signals through TNFR1 and TNFR2. TNF-β is produced by activated T and B lymphocytes, and has similar activities to TNF-α. Like TNF-α, TNF-β is involved in the regulation of various biological processes, including cell proliferation, differentiation, apoptosis, lipid metabolism, coagulation, and neurotransmission. TNF-β is secreted as a soluble polypeptide, but can form heterotrimers with lymphotoxin-β, which effectively anchors the TNF-β to the cell surface. TNF-β is cytotoxic to a wide range of tumor cells. Recombinant Human TNF-β is a secreted 172 amino acid protein (18.6 kDa) which forms an active non-disulfide-linked homotrimer structure in solution.别名:Tumor Necrosis Factor-β, TNFSF1B, Lymphotoxin-alpha (LT-α)氨基酸序列:MLPGVGLTPS AAQTARQHPK MHLAHSTLKP AAHLIGDPSK QNSLLWRANT DRAFLQDGFS LSNNSLLVPT SGIYFVYSQV VFSGKAYSPK ATSSPLYLAH EVQLFSSQYP FHVPLLSSQK MVYPGLQEPW LHSMYHGAAF QLTQGDQLST HTDGIPHLVL SPSTVFFGAF AL来源:E.coli纯度:Greater than 98% by SDS-PAGE gel and HPLC analyses.生物活性:TheED50as determined by the cytolysis of murine L929 cells in the presence of Actinomycin-D is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107units/mg.Calculated Molecular Weight:18.6 kDaAccession Number:P01374Gene ID:4049Note:1mg will be provided as 2x500μg.交叉反应:Human,Mouse原产地:USA仅用于科研，不能用于临床和诊断。 |
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