Anti-Human/Mouse MCP-1 (CCL2) SAFIRE Purified

2024-10-15

Anti-Human/Mouse MCP-1 (CCL2) SAFIRE Purified

货号:80111-25-50,80111-25-500

规格:50 μg,500 μg

价格:1100,3410

产品类型:流式抗体

品牌:Biogems

物种:人/小鼠/大鼠

宿主:Armenian hamster仓鼠

抗体亚型:IgG

荧光染料:Purified

Catalogue Number :80111-25

Description

The 2H5 monoclonal antibody specifically reacts with mouse, rat, human MCP-1 (Monocyte Chemoattractant Protein-1), also known as CCL2 and MCAF (Monocyte Chemotactic and Activating Factor). MCP-1 is a C-C (beta) chemokine that regulates cytokine production in monocytes and the expression of adhesion molecules. The 2h5 antibody can neutralize the bioactivity of recombinant or natural MCP-1.

Additional Information

Clone

2H5

Format:

SAFIRE Purified

Applications

FC, FA, Neutralization

Reactivity

Human, Mouse, Rat

Isotype:

Armenian Hamster IgG

Research Interest:Chemotaxis,Angiogenesis
Cell Type:Dendritic Cells,Monocytes and Macrophages,T Cells

Preperation:

The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.

Formulation:

Phosphate-buffered aqueous solution, ph7.2.

References:

Luo, Y., Laning, J., Hayashi, M., Hancock, P. R., Rollins, B., & Dorf, M. E. (1994). Serologic analysis of the mouse beta chemokine JE/monocyte chemoattractant protein-1.The Journal of immunology,153(8), 3708-3716.

Bost, K. L., Bento, J. L., Petty, C. C., Schrum, L. W., Hudson, M. C., & Marriott, I. (2001). Monocyte chemoattractant protein-1 expression by osteoblasts following infection with Staphylococcus aureus or Salmonella.Journal of Interferon & Cytokine Research,21(5), 297-304.

Taal, M. W., Chertow, G. M., Rennke, H. G., Gurnani, A., Jiang, T., Shahsafaei, A., ... & Mackenzie, H. S. (2001). Mechanisms underlying renoprotection during renin-angiotensin system blockade.American Journal of Physiology-Renal Physiology,280(2), F343-F355.

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