Clone

MTS510

Format:

SAFIRE Purified

Applications

FC, FA

Reactivity

Mouse

Isotype:

Rat IgG2a, kappa

Preperation:

The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.

Formulation:

Phosphate-buffered aqueous solution, ph7.2.

References:

Akashi, S., Saitoh, S. I., Wakabayashi, Y., Kikuchi, T., Takamura, N., Nagai, Y., ... & Miyake, K. (2003). Lipopolysaccharide Interaction with Cell Surface Toll-like Receptor 4-MD-2 Higher Affinity than That with MD-2 or CD14.The Journal of experimental medicine,198(7), 1035-1042.

Qi, H. Y., & Shelhamer, J. H. (2005). Toll-like receptor 4 signaling regulates cytosolic phospholipase A2 activation and lipid generation in lipopolysaccharide-stimulated macrophages.Journal of Biological Chemistry,280(47), 38969-38975.

Shimazu, R., Akashi, S., Ogata, H., Nagai, Y., Fukudome, K., Miyake, K., & Kimoto, M. (1999). MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4.The Journal of experimental medicine,189(11), 1777-1782.