Clone

HM40-3

Format:

SAFIRE Purified

Applications

FC, FA

Reactivity

Mouse, Rat

Isotype:

Armenian Hamster IgM, kappa

Research Interest:

Adaptive Immunity

Cell Type:

B Cells,Dendritic Cells,NK and NKT Cells,Monocytes and Macrophages

Preperation:

The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.

Formulation:

Phosphate-buffered aqueous solution, ph7.2.

References:

Kaneko, Y., Hirose, S., Abe, M., Yagita, H., Okumura, K., & Shirai, T. (1996). CD40‐mediated stimulation of B1 and B2 cells: implication in autoantibody production in murine lupus.European journal of immunology,26(12), 3061-3065.

Ferlin, W. G., Severinson, E., Ström, L., Heath, A. W., Coffman, R. L., Ferrick, D. A., & Howard, M. C. (1996). CD40 signaling induces interleukin‐4‐independent IgE switching in vivo.European journal of immunology,26(12), 2911-2915.

Kashiwada, M., Kaneko, Y., Yagita, H., Okumura, K., & Takemori, T. (1996). Activation of mitogen‐activated protein kinases via CD40 is distinct from that stimulated by surface IgM on B cells.European journal of immunology,26(7), 1451-1458.