Clone

UIC2

Format:

PE

Applications

FC

Reactivity

Human

Isotype:

Mouse IgG2a

Preperation:

The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Formulation:

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

References:

Mechetner, E. B., & Roninson, I. B. (1992). Efficient inhibition of P-glycoprotein-mediated multidrug resistance with a monoclonal antibody.Proceedings of the National Academy of Sciences,89(13), 5824-5828.

Chaudhary, P. M., Mechetner, E. B., & Roninson, I. B. (1992). Expression and activity of the multidrug resistance P-glycoprotein in human peripheral blood lymphocytes [see comments].Blood,80(11), 2735-2739.

Goda, K., Fenyvesi, F., Bacsó, Z., Nagy, H., Márián, T., Megyeri, A., ... & Szabó, G. (2007). Complete inhibition of P-glycoprotein by simultaneous treatment with a distinct class of modulators and the UIC2 monoclonal antibody.Journal of Pharmacology and Experimental Therapeutics,320(1), 81-88.