CD57 Monoclonal Antibody (TB01 (TBO1)), Functional Grade, eBioscience™/CD57 单克隆 (TB01 (TBO1)), 功能抗体, eBioscience™

货号：16-0577-85,16-0577-025,16-0577-050

规格：500 µg,25 mg,50 mg

价格：3298,72266,120443

产品类型：流式抗体

品牌：eBioscience

抗原：CD57

物种：人

宿主：小鼠

抗体亚型：IgM

克隆号：TB01 (TBO1)

荧光染料：其它

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类型:	一抗(功能抗体）	同型对照：
浓度：	1 mg/mL	用法：	1 µg/test（Flow）;Assay-Dependent（对照）;Assay-Dependent（功能检测）

产品详细信息Description: This TB01 monoclonal antibody reacts with human CD57 (also known as HNK-1 and Leu-7), a 110-kDa cell surface glycoprotein expressed on a subset of natural killer (NK) cells and NK T cells.Applications Reported: This TB01 antibody has been reported for use in flow cytometric analysis.Applications Tested: This TB01 (TBO1) antibody has been tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at less than or equal to 1 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Storage and handling: Use in a sterile environment.Filtration: 0.2 µm post-manufacturing filtered.Purity: Greater than 90%, as determined by SDS-PAGE.Endotoxin Level: Less than 0.001 ng/µg antibody, as determined by LAL assay.Aggregation: Less than 10%, as determined by HPLC.靶标信息The protein encoded by this gene is a member of the glucuronyltransferase gene family. These enzymes exhibit strict acceptor specificity, recognizing nonreducing terminal sugars and their anomeric linkages. This gene product functions as the key enzyme in a glucuronyl transfer reaction during the biosynthesis of the carbohydrate epitope HNK-1 (human natural killer-1, also known as CD57 and LEU7). Alternate transcriptional splice variants have been characterized.仅用于科研。不用于诊断过程。

数据

CD57 Antibody (16-0577-85)Cell reports 2017 -Published figure using CD57 monoclonal antibody (Product # 16-0577-85)

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参考文献：

IF1.Cell reportsMass Cytometric Analysis of HIV Entry, Replication, and Remodeling in Tissue CD4+ T Cells."Published figure using CD57 monoclonal antibody (Product # 16-0577-85) in Flow Cytometry"2.AutophagyA novel method for autophagy detection in primary cells: impaired levels of macroautophagy in immunosenescent T cells."Published figure using CD57 monoclonal antibody (Product # 16-0577-85) in Flow Cytometry"流式3.Nature communicationsUnique transcriptional and protein-expression signature in human lung tissue-resident NK cells."16-0577 was used in Flow cytometry/Cell sorting to indicate that human lung trNK cells have distinct features, likely regulating their function in barrier immunity."AuthorsMarquardt N,Kekäläinen E,Chen P,Lourda M,Wilson JN,Scharenberg M,Bergman P,Al-Ameri M,Hård J,Mold JE,Ljunggren HG,Michaëlsson J4.Blood advancesTCF1 expression marks self-renewing human CD8+T cells."16-0577 was used in Flow cytometry/Cell sorting to show analyses of TCF1 expression from patient specimens may become a useful biomarker for adaptive immune function in response to vaccination, infection, autoimmunity, and cancer."AuthorsKratchmarov R,Magun AM,Reiner SL5.AutophagyA novel method for autophagy detection in primary cells: impaired levels of macroautophagy in immunosenescent T cells."Published figure using CD57 monoclonal antibody (Product # 16-0577-85) in Flow Cytometry"

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