| 产品介绍 | | |
| Mouse anti hCG antibody, clone INN-hCG-2recognizes the beta 1 epitope on human chorionic gonadotrophin (hCG).Chorionic gonadotrophin is a member of the glycoprotein hormone family that is synthesized by the placenta throughout pregnancy. The glycoprotein hormone family has 4 members, the other three being luteinising hormone (LH), follicle stimulating hormone (FSH) and thyroid stimulating hormone (TSH). All consist of two subunits, alpha and beta. The alpha subunit is highly homologous between family members.Mouse anti hCG antibody, clone INN-hCG-2 is reactive with hCG, hCGbeta, hCGbetacf (fragment), hCGn (nicked), hCGbetan, and CTP-hCG. No cross reaction is observed with hLH, hLHbeta, hFSH, hTSH, or the glycoprotein hormone alpha chains. |
| 产品详情 | | |
| Target Species | Human |
| Product Form | Purified IgG - liquid |
| Preparation | Purified IgG prepared by affinity chromatography on Protein A |
| Buffer Solution | Phosphate buffered saline |
| Immunogen | Spleen cells from an immunised BALB/c mouse were fused with the mouse P3-NS1/1 - Ag 4.1 myeloma cell line. |
| Approx. Protein Concentrations | IgG concentration 1.0 mg/ml |
| Regulatory | For research purposes only |
| Guarantee | 12 months from date of despatch |
| 存储条件 | | |
| Store at +4℃. DO NOT FREEZE.This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use. |
| 应用 | | |
| Application Name | Verified | Min Dilution | Max Dilution |
| Flow Cytometry | √ | | |
| This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. |
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| 文献 |
| 1.Kofler, R.et al.(1982) Monoclonal antibodies against human chorionic gonadotropin (hCG): I. production, specificity, and intramolecular binding sites.Am J Reprod Immunol. 2 (4): 212-6.2.Berger, P.et al.(1993) Variants of human chorionic gonadotropin from pregnant women and tumor patients recognized by monoclonal antibodies.J Clin Endocrinol Metab. 77 (2): 347-51.3.Zimmermann, G.et al.(2009) Zimmermann G, Ackermann W, Alexander H. Epithelial human chorionic Epithelial human chorionic gonadotropin is expressed and produced in human secretory endometrium during the normal menstrual cycle. Biol Reprod. 2009 May;80(5):1053-65. Epub 2009 Jan 21. PubMed PMID: 19164178.Biol Reprod. 80:1053-65. |
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