ANTI-HUMAN CD45 (2D1) APC

2024-10-17

ANTI-HUMAN CD45 (2D1) APC

货号:17-9459-42,17-9459-41

规格:100T,25T

价格:2996,1183

产品类型:流式抗体

品牌:eBioscience

抗原:CD45

物种:人

宿主:小鼠

抗体亚型:IgG

克隆号:2D1

荧光染料:APC

抗体类型:单抗同型对照:Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), APC
免疫原性:用法:5uL(0.25µg)/test(Flow)
Description: The 2D1 monoclonal antibody reacts with all isoforms of human CD45, also known as Leukocyte Common Antigen (LCA). CD45 is expressed by all hematopoietic cells excluding circulating erythrocytes and platelets. The cytoplasmic portion of CD45 has tyrosine phosphatase enzymatic activity and plays an important role in activation of lymphocytes.Applications Reported: This 2D1 antibody has been reported for use in flow cytometric analysis.Applications Tested: This 2D1 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 µL (0.25 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser.Filtration: 0.2 µm post-manufacturing filtered.
数据

CD45 Antibody (17-9459-42) in FlowStaining of normal human peripheral blood cells with Mouse IgG1 K Isotype Control APC (Product # 17-4714-81) (blue histogram) or Anti-Human CD45 APC (purple histogram). Cells in the lymphocyte gate were used for analysis.
推荐产品:
间充干细胞MSC分选间充干细胞MSC扩增、分化培养基CD73流式抗体细胞因子
参考文献:
1.Cell researchBlocking the recruitment of naive CD4+ T cells reverses immunosuppression in breast cancer.2017"17-9459 was used in Flow cytometry/Cell sorting to demonstrate that blocking PITPNM3 recognition of CCL18 could be an attractive immunotherapy aproach for treating breast cancer."Authors Su S,Liao J,Liu J,Huang D,He C,Chen F,Yang L,Wu W,Chen J,Lin L,Zeng Y,Ouyang N,Cui X,Yao H,Su F,Huang JD,Lieberman J,Liu Q,Song E2.Cancer immunology researchPD-1+Tim-3+ CD8+ T Lymphocytes Display Varied Degrees of Functional Exhaustion in Patients with Regionally Metastatic Differentiated Thyroid Cancer.2015"17-9459 was used in Flow cytometry/Cell sorting to determine that the release of PD-1 and Tim-3, and the inhibition of Tregs, may encourage tumour elimination in metastatic differentiated thyroid cancer."Authors Severson JJ,Serracino HS,Mateescu V,Raeburn CD,McIntyre RC,Sams SB,Haugen BR,French JD3.Cell metabolismA Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan.2015"17-9459 was used in Flow cytometry/Cell sorting to study the effect of prolonged fasting on promoting multi-system regeneration, enhancing cognitive performance, and altering healthspan."Authors Brandhorst S,Choi IY,Wei M,Cheng CW,Sedrakyan S,Navarrete G,Dubeau L,Yap LP,Park R,Vinciguerra M,Di Biase S,Mirzaei H,Mirisola MG,Childress P,Ji L,Groshen S,Penna F,Odetti P,Perin L,Conti PS,Ikeno Y,Kennedy BK,Cohen P,Morgan TE,Dorff TB,Longo VD4.BloodJAK2/STAT5 inhibition by nilotinib with ruxolitinib contributes to the elimination of CML CD34+ cells in vitro and in vivo.2014"17-9459 was used in Flow cytometry/Cell sorting to investigate how JAK2/STAT5 inhibition by nilotinib with ruxolitinib contributes to the elimination of CML CD34+ cells in vitro and in vivo."Authors Gallipoli P,Cook A,Rhodes S,Hopcroft L,Wheadon H,Whetton AD,Jørgensen HG,Bhatia R,Holyoake TL5.GastroenterologyExpression of intercellular adhesion molecule 1 by hepatocellular carcinoma stem cells and circulating tumor cells.2013"17-9459 was used in Flow cytometry/Cell sorting to demonstrate that the stem cell factor Nanog regulates expression of ICAM-1 in hepatocellular carcinoma cells."Authors Liu S,Li N,Yu X,Xiao X,Cheng K,Hu J,Wang J,Zhang D,Cheng S,Liu S

技术参数

产品应用 Flow

© Bio-Rad伯乐代理官网-伯乐抗体-伯乐层析Aminex色谱柱是专业的授权总代理区域代理经销平台。
© 如需询价,请加客服QQ:1749072012 、客服微信:jinshanbio,或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务,数据资源基于CC协议。
© 本文地址:https://biorod.cn/thread-16689.htm
产品询价需求提交
返回
扫码添加客服微信,咨询产品报价