1.Cell researchBlocking the recruitment of naive CD4+ T cells reverses immunosuppression in breast cancer.2017"17-9459 was used in Flow cytometry/Cell sorting to demonstrate that blocking PITPNM3 recognition of CCL18 could be an attractive immunotherapy aproach for treating breast cancer."Authors Su S,Liao J,Liu J,Huang D,He C,Chen F,Yang L,Wu W,Chen J,Lin L,Zeng Y,Ouyang N,Cui X,Yao H,Su F,Huang JD,Lieberman J,Liu Q,Song E2.Cancer immunology researchPD-1+Tim-3+ CD8+ T Lymphocytes Display Varied Degrees of Functional Exhaustion in Patients with Regionally Metastatic Differentiated Thyroid Cancer.2015"17-9459 was used in Flow cytometry/Cell sorting to determine that the release of PD-1 and Tim-3, and the inhibition of Tregs, may encourage tumour elimination in metastatic differentiated thyroid cancer."Authors Severson JJ,Serracino HS,Mateescu V,Raeburn CD,McIntyre RC,Sams SB,Haugen BR,French JD3.Cell metabolismA Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan.2015"17-9459 was used in Flow cytometry/Cell sorting to study the effect of prolonged fasting on promoting multi-system regeneration, enhancing cognitive performance, and altering healthspan."Authors Brandhorst S,Choi IY,Wei M,Cheng CW,Sedrakyan S,Navarrete G,Dubeau L,Yap LP,Park R,Vinciguerra M,Di Biase S,Mirzaei H,Mirisola MG,Childress P,Ji L,Groshen S,Penna F,Odetti P,Perin L,Conti PS,Ikeno Y,Kennedy BK,Cohen P,Morgan TE,Dorff TB,Longo VD4.BloodJAK2/STAT5 inhibition by nilotinib with ruxolitinib contributes to the elimination of CML CD34+ cells in vitro and in vivo.2014"17-9459 was used in Flow cytometry/Cell sorting to investigate how JAK2/STAT5 inhibition by nilotinib with ruxolitinib contributes to the elimination of CML CD34+ cells in vitro and in vivo."Authors Gallipoli P,Cook A,Rhodes S,Hopcroft L,Wheadon H,Whetton AD,Jørgensen HG,Bhatia R,Holyoake TL5.GastroenterologyExpression of intercellular adhesion molecule 1 by hepatocellular carcinoma stem cells and circulating tumor cells.2013"17-9459 was used in Flow cytometry/Cell sorting to demonstrate that the stem cell factor Nanog regulates expression of ICAM-1 in hepatocellular carcinoma cells."Authors Liu S,Li N,Yu X,Xiao X,Cheng K,Hu J,Wang J,Zhang D,Cheng S,Liu S |