ANTI-HU CD105 (ENDOGLIN)(SN6) PE

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ANTI-HU CD105 (ENDOGLIN)(SN6) PE

货号:12-1057-41,12-1057-42

规格:25T,100T

价格:1067,2377

产品类型:流式抗体

品牌:eBioscience

抗原:CD105

物种:人

宿主:小鼠

抗体亚型:IgG1, kappa

克隆号:SN6

荧光染料:PE

抗体类型:单抗同型对照:IgG1, kappa
免疫原性:用法:5uL(1 µg)/test(Flow)
Description: The SN6 monoclonal antibody reacts with human CD105, also known as Endoglin. CD105, an approximately 90 kDa disulfide-linked homodimer is expressed by vascular endothelial cells and some bone marrow cells and activated macrophages. It is suggested that CD105 functions in adhesion and embryonic angiogenesis.Applications Reported: The SN6 antibody has been reported for use in flow cytometric analysis.Applications Tested: The SN6 antibody has been pre-titrated and tested by flow cytometric analysis of the U937 cell line. This can be used at 5 µL (1 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.Filtration: 0.2 µm post-manufacturing filtered.
数据

CD105 (Endoglin) Antibody (12-1057-41) in FlowStaining of U937 cells with Mouse IgG1 K Isotype Control PE (Product # 12-4714-81) (blue histogram) or Anti-Human CD105 (Endoglin) PE (purple histogram). Total viable cells, as determined by Fixable Viability Dye eFluor® 780, were used for analysis.
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参考文献:
1.Stem cell researchImpaired function of bone marrow stromal cells in systemic mastocytosis.2015"12-1057 was used in Flow cytometry/Cell sorting to implicate epigenetic change in mesenchymal stem cells as a driver of some of the symptoms associated with systemic mastocytosis."Authors Nemeth K,Wilson TM,Ren JJ,Sabatino M,Stroncek DM,Krepuska M,Bai Y,Robey PG,Metcalfe DD,Mezey E2.NPJ Regenerative medicineCRISPR/Cas9-based genetic correction for recessive dystrophic epidermolysis bullosa.2018"12-1057 was used in Flow cytometry/Cell sorting to showcase the therapeutic potential of gene-editing coupled with stem cell technology for the treatment of recessive dystrophic epidermolysis bullosa."Authors Webber BR,Osborn MJ,McElroy AN,Twaroski K,Lonetree CL,DeFeo AP,Xia L,Eide C,Lees CJ,McElmurry RT,Riddle MJ,Kim CJ,Patel DD,Blazar BR,Tolar J3.Stem cell research and therapyHuman umbilical cord mesenchymal stem cells improve the reserve function of perimenopausal ovary via a paracrine mechanism.2017"12-1057 was used in Flow cytometry/Cell sorting to investigate the potential of hUCMSCs in improving ovarian function and withstanding ovarian senescence."Authors Li J,Mao Q,He J,She H,Zhang Z,Yin C4.Stem cell research and therapyHuman umbilical cord mesenchymal stem cells improve the reserve function of perimenopausal ovary via a paracrine mechanism.2017"12-1057 was used in Flow cytometry/Cell sorting to investigate the potential of hUCMSCs in improving ovarian function and withstanding ovarian senescence."Authors Li J,Mao Q,He J,She H,Zhang Z,Yin C5.Scientific reportsPotency of umbilical cord blood- and Wharton's jelly-derived mesenchymal stem cells for scarless wound healing.2016"12-1057 was used in Flow cytometry/Cell sorting to determine that umbilical cord blood offers a potential source of MSCs for therapeutic scarless wound healing."Authors Doi H,Kitajima Y,Luo L,Yan C,Tateishi S,Ono Y,Urata Y,Goto S,Mori R,Masuzaki H,Shimokawa I,Hirano A,Li TS

技术参数

产品应用 Flow;ICC

细胞类型 MSC

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