| 1.Circulation researchEfficient gene disruption in cultured primary human endothelial cells by CRISPR/Cas9."14-0458 was used in Flow cytometry/Cell sorting to demonstrate that the CRISPR/Cas9 modification of epithelial cells is a powerful platform for vascular research and for regenerative medicine."Authors Abrahimi P,Chang WG,Kluger MS,Qyang Y,Tellides G,Saltzman WM,Pober JS2.Nature medicineAutosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations."14-0458 was used in Flow cytometry/Cell sorting to demonstrate the consequences for mice with mutations in CTLA4, an essential negative regulator of immune responses."Authors Schubert D,Bode C,Kenefeck R,Hou TZ,Wing JB,Kennedy A,Bulashevska A,Petersen BS,Schäffer AA,Grüning BA,Unger S,Frede N,Baumann U,Witte T,Schmidt RE,Dueckers G,Niehues T,Seneviratne S,Kanariou M,Speckmann C,Ehl S,Rensing-Ehl A,Warnatz K,Rakhmanov M,Thimme R,Hasselblatt P,Emmerich F,Cathomen T,Backofen R,Fisch P,Seidl M,May A,Schmitt-Graeff A,Ikemizu S,Salzer U,Franke A,Sakaguchi S,Walker LSK,Sansom DM,Grimbacher B3.British journal of cancerPD-1(+) CD8(+) T cells are exhausted in tumours and functional in draining lymph nodes of colorectal cancer patients."14-0458 was used in Flow cytometry/Cell sorting to evaluate the role of PD-1-PD-L1 pathway in CD8(+) T-cell functions in tumour-draining lymph nodes (TDLNs) and tumours of CRC patients."Authors Wu X,Zhang H,Xing Q,Cui J,Li J,Li Y,Tan Y,Wang S4.Journal of immunology (Baltimore, Md. : 1950)Helios+ and Helios- cells coexist within the natural FOXP3+ T regulatory cell subset in humans."14-0458 was used in Flow cytometry/Cell sorting to investigate the link between Helios expression and natural regulatory FOXP3+ T cell subsets from different origins in humans."Authors Himmel ME,MacDonald KG,Garcia RV,Steiner TS,Levings MK5.PloS oneNovel serial positive enrichment technology enables clinical multiparameter cell sorting."14-0458 was used in Flow cytometry/Cell sorting to exhibit novel, low-affinity antibody-derived Fab-fragments for use in clinical cell preparations and research."Authors Stemberger C,Dreher S,Tschulik C,Piossek C,Bet J,Yamamoto TN,Schiemann M,Neuenhahn M,Martin K,Schlapschy M,Skerra A,Schmidt T,Edinger M,Riddell SR,Germeroth L,Busch DH |
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