Nkx2.5 Polyclonal Antibody

货号：PA5-47322

规格：100 µg

价格：5335

产品类型：免疫组化一抗

品牌：eBioscience

物种：人

宿主：山羊

抗体亚型：IgG

荧光染料：Purified

类型:	多抗	同型对照：
浓度：	0.2 mg/mL	用法：	5-15 µg/mL（IHC）；0.1 g/mL(WB)
免疫原性：	E. coli-derived recombinant human NKX2.5 Gln24-Arg137

产品详细信息Reconstitute at 0.2 mg/mL in sterile PBS.靶标信息NKX2-5 is a transcription factor protein which plays a crucial role in cardiac development and differentiation. It is a low molecular weight protein of 35-38 kDa depending on phosphorylation status. Expression is mainly restricted to the heart. But during embryogenesis NKX2-5 expression has also been detected in spleen-precursor cells. Over expression of NKX2-5 resulted in expression of neuronal markers in C2C12 murine myogenic cells. Functionally it is involved in differentiation processes in heart development and in homeostasis and survival of cardiac myocytes as well maintains the initial muscle differentiation paradigm.

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