MAPK Family Activation Multispecies InstantOne ELISA Kit/多物种MAPK家族InstantOne ELISA试剂盒-Bio-Rad-Bio-Rad伯乐代理官网-伯乐抗体-伯乐层析Aminex色谱柱

MAPK Family Activation Multispecies InstantOne ELISA Kit/多物种MAPK家族InstantOne ELISA试剂盒

2024-10-17

MAPK Family Activation Multispecies InstantOne ELISA Kit/多物种MAPK家族InstantOne ELISA试剂盒

货号：85-86195-11

规格：96 tests

价格：8078

产品类型：InstantOne ELISA

品牌：Thermo Fisher

物种：其它

宿主：其它

抗体亚型：其它

荧光染料：其它

样本类型/体积	细胞裂解液 20μL
操作时间	1 hr 20 min
测试时间	1 hr 10 min
Homogenous (no wash)	No
仪器设备	Colorimetric microplate reader 酶标仪
规格	96 Tests
组份	- 捕获抗体 - 检测抗体 - InstantOne 检测板 - 细胞裂解液 - 增强剂溶液 - 洗涤液（10X） - 底物试剂（TMB） - 终止液 - 阳性对照细胞裂解物（冻干） - 密封条
储存温度	2-8℃
Protein name	JNK1/JNK2/JNK3/ERK1/2/p38 MAPK alpha
物种（Tested）	人
试剂盒类型	InstantOne ELISA
检测抗体偶联物	Biotin
标记（染料）	HRP
Gene ID	(Human) 1432,(Human) 5595,(Human) 5599,(Human) 5594
Gene symbol	MAPK14, MAPK3, MAPK8, MAPK1
Gene aliases	CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c, ERK, ERK-2, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk, p42-MAPK
UniProt ID	(Human) Q8TDX0,(Human) P27361,(Human) P45983,(Human) P28482

The InstantOne™ ELISA is specifically engineered for accurate measurement of phosphorylated ERK 1/2 (human, mouse, hamster), p38 MAPK (human, mouse), and JNK 1/2 (human, mouse) in cell lysates. Detection of these phosphorylated molecules in rat is also expected. The InstantOne™ ELISA kit allows for fast analysis of samples in approximately one hour. All reagents used in a traditional sandwich ELISA are added in solution to a plate followed by a wash step and detection with the TMB colorimetric substrate.InstantOne™ELISA是专为精确测量细胞裂解物中磷酸化ERK 1/2（人类，小鼠，仓鼠），p38 MAPK（人类，小鼠）和JNK 1/2（人类，小鼠）而设计的。还期望在大鼠中检测到这些磷酸化分子。 InstantOne™ELISA试剂盒可在大约一小时内快速分析样品。将传统的夹心ELISA中使用的所有试剂均以溶液形式添加到板上，然后进行洗涤步骤，并使用TMB比色底物进行检测。Target information 靶标信息MAP kinases play a significant role in many biological processes, including cell adhesion and spreading, cell differentiation and apoptosis. MAPKBP-1 (mitogen-activated protein kinase binding protein 1), also known as JNKBP-1, is a 1,514 amino acid protein that contains twelve WD repeats. Induced by TRAF2 (TNF receptor-associated factor 2) and Tak1 (TGF-β-activated kinase 1), MAPKBP-1 is thought to act an adaptor protein for NFκB (nuclear factor κ-B) activation. MAPKBP-1 interacts with JNK3 and may promote TRAF2 polyubiquitination. MAPKBP-1 exists as six alternatively spliced variants and is encoded by a gene located on human chromosome 15. Human chromosome 15 houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.MAP激酶在许多生物学过程中起重要作用，包括细胞粘附和扩散，细胞分化和凋亡。 MAPKBP-1（促分裂原激活的蛋白激酶结合蛋白1），也称为JNKBP-1，是一个1,514个氨基酸的蛋白质，包含十二个WD重复序列。通过TRAF2（TNF受体相关因子2）和Tak1（TGF-β活化激酶1）诱导，MAPKBP-1被认为是NFκB（核因子κ-B）活化的衔接蛋白。 MAPKBP-1与JNK3相互作用并可能促进TRAF2多聚泛素化。 MAPKBP-1以六个可变剪接变体形式存在，由位于人类15号染色体上的一个基因编码。人类15号染色体容纳700多个基因，占人类基因组的近3％。 Angelman综合征，Prader-Willi综合征，Tay-Sachs病和Marfan综合征均与15号染色体局部基因的缺陷有关。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用，不用于诊断过程，未经明确授权不得转售。

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MAPK Family Activation Multispecies InstantOne ELISA Kit/多物种MAPK家族InstantOne ELISA试剂盒

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