CD9 Polyclonal Antibody/CD9多克隆抗体

货号：PA5-85955

规格：100 µL

价格：4806

产品类型：免疫组化一抗

品牌：Thermo Fisher

抗原：Synthetic peptide corresponding to N-terminal of H

物种：人/小鼠/大鼠

宿主：兔

抗体亚型：IgG

荧光染料：其它

类型:	多抗	同型对照：
浓度：	1 mg/mL	用法：	1:100-1:200(Flow);1:200(ICC);1:200(IF);1:200(IHC);1:1,000(WB)

靶标信息CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophil, stimulated T lymphocytes and by neurons and glial cells in the peripheral nervous system. CD9 belongs to a family of membrane proteins termed tetraspanins which transverse the membrane four times. In pre B cells and platelets, CD9 antigen regulates cell activation and aggregation possibly through an association with the integrin CD41 / CD61 (GPIIb / GPIIIa). CD9 is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion, plays roles in cell attachment and proliferation and is necessary for association of heterologous MHC II molecules on the dendritic cell plasma membrane which is important for effective T cell stimulation. CD9 functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression plays a critical role in the suppression of cancer cell motility and metastasis. CD9 is also considered as metastasis suppressor in solid tumors.

数据

CD9 Antibody (PA5-85955) in FlowFlow Cytometric analysis of CD9 in Jurkat cells using a CD9 Polyclonal Antibody (Product # PA5-85955) at a dilution of 1:100, as seen in blue compared with an unlabelled control (cells without incubation with primary antibody; red). Goat anti rabbit IgG (FITC) was used as the secondary antibody. CD9 Antibody (PA5-85955) in IHC (P)Immunohistochemical analysis of CD9 of paraffin-embedded Mouse large intestine tissue using a CD9 Polyclonal antibody (Product #PA5-85955). Counter stained with hematoxylin.

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技术参数

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