CD57 Monoclonal Antibody (TB01 (TBO1)), FITC

货号：11-0577-41,11-0577-42

规格：25 Tests,100 Tests

价格：1065,2136

产品类型：流式抗体

品牌：eBioscience

抗原：CD57

物种：人

宿主：小鼠

抗体亚型：IgM

克隆号：TB01 (TBO1)

荧光染料：FITC

类型:	单抗	同型对照：	Mouse IgM Isotype Control (11E10), FITC
浓度：	5 µL/Test	用法：	5 μL (1 μg)/test(Flow)

产品详细信息Description: This TB01 monoclonal antibody reacts with human CD57 (also known as HNK-1 and Leu-7), a 110-kDa cell surface glycoprotein expressed on a subset of natural killer (NK) cells and NK T cells.Applications Reported: The TB01 (TBO1) antibody has been reported for use in flow cytometric analysis.Applications Tested: This TB01 (TBO1) antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 µL (1 µg)per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser.Filtration: 0.2 µm post-manufacturing filtered.靶标信息The protein encoded by this gene is a member of the glucuronyltransferase gene family. These enzymes exhibit strict acceptor specificity, recognizing nonreducing terminal sugars and their anomeric linkages. This gene product functions as the key enzyme in a glucuronyl transfer reaction during the biosynthesis of the carbohydrate epitope HNK-1 (human natural killer-1, also known as CD57 and LEU7). Alternate transcriptional splice variants have been characterized.

数据

CD57 Antibody (11-0577-41) in FlowStaining of normal human peripheral blood cells with Anti-Human CD56 (NCAM) APC (Product # 17-0567-42) and Mouse IgM Isotype Control FITC (Product # 11-4752-80) (left) or Anti-Human CD57 FITC (right). Cells in the lymphocyte gate were used for analysis.

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参考文献：

1.Stem cells (Dayton, Ohio)Comprehensive Cell Surface Antigen Analysis Identifies Transferrin Receptor Protein-1 (CD71) as a Negative Selection Marker for Human Neuronal Cells.2.Cell reportsMass Cytometric Analysis of HIV Entry, Replication, and Remodeling in Tissue CD4+ T Cells."Published figure using CD57 monoclonal antibody (Product # 11-0577-42) in Flow Cytometry"3.PLoS pathogensActivation of Innate and Adaptive Immunity by a Recombinant Human Cytomegalovirus Strain Expressing an NKG2D Ligand."11-0577 was used in Flow cytometry/Cell sorting to investigate a strategy for an HCMV vaccine that aims at the simultaneous activation of innate and adaptive immune responses."AuthorsTomić A,Varanasi PR,Golemac M,Malić S,Riese P,Borst EM,Mischak-Weissinger E,Guzmán CA,Krmpotić A,Jonjić S,Messerle M4.PloS oneCommon gamma chain cytokines promote rapid in vitro expansion of allo-specific human CD8+ suppressor T cells."11-0577 was used in Flow cytometry/Cell sorting to demonstrate the use of common γc cytokines in combination with donor APCs as a strategy for generation of donor-specific T cells for immunotherapy."AuthorsYu Y,Zitzner JR,Houlihan J,Herrera N,Xu L,Miller J,Mathew JM,Tambur AR,Luo X5.Disease markersImmunosenescent CD57+CD4+ T-cells accumulate and contribute to interferon-γ responses in HIV patients responding stably to ART."11-0577 was used in Flow cytometry/Cell sorting to determine the key factors influencing the pathogenesis of secondary viral infections in HIV patients receiving ART."AuthorsFernandez S,French MA,Price P

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