Human ILT-2/LIR-1/CD85j ELISA Kit/人ILT-2 / LIR-1 / CD85j ELISA试剂盒
货号：EH277RB,EH277RBX5,EH277RBX10
规格：96 tests,5X96 tests,10X96 tests
价格：6641,29884,57271
产品类型：Platinum ELISA
品牌：Thermo Fisher
物种：人
宿主：其它
抗体亚型：其它
荧光染料：其它
灵敏度 | 22 pg/mL |
| 检测范围 | 22-5,000 pg/mL |
样本类型/体积 | 血清 50 μL 血浆 50 μL 上清液 50 μL |
操作时间 | 1 hr 20 min |
测试时间 | 4 hr 45 min |
Homogenous (no wash) | No |
| 批间变异系数（CV） | <12% |
| 批内变异系数（CV） | <10% |
仪器设备 | Colorimetric Microplate Reader 酶标仪 |
规格 | 5 x 96 Tests |
组份 | - 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖 |
储存温度 | 2-8℃ |
| Protein name | CD85j (ILT2) |
| Protein aliases | CD85 antigen-like family member J, CD85j, Ig-like transcript 2, ILT-2, Immunoglobulin-like transcript 2, leucocyte Ig-like receptor B1, Leukocyte immunoglobulin-like receptor subfamily B member 1, leukocyte immunoglobulin-like receptor subfamily B member 1 soluble isoform, leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1, LIR-1, MIR-7, Monocyte/macrophage immunoglobulin-like receptor 7, myeloid inhibitory receptor 7 |
物种（Tested） | 人 |
试剂盒类型 | Sandwich ELISA Kit |
标记（染料） | HRP |
| 检测抗体偶联物 | Biotin |
| Gene aliases | CD85J, ILT-2, ILT2, LILRB1, LIR-1, LIR1, MIR-7, MIR7, PIR-B, PIRB |
| Gene ID | (Human) 10859 |
| Gene symbol | LILRB1 |
| UniProt ID | (Human) Q8NHL6 |
| Human ILT-2/LIR-1/CD85j quantitates human ILT-2/LIR-1/CD85j in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human ILT-2/LIR-1/CD85j.人ILT-2 / LIR-1 / CD85j定量分析血清，血浆，上清液中的人ILT-2 / LIR-1 / CD85j。 该检测试剂盒将专门识别天然和重组人ILT-2 / LIR-1 / CD85j。Target information 靶标信息This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.该基因是白细胞免疫球蛋白样受体（LIR）家族的成员，该家族在染色体区域19q13.4的基因簇中发现。 编码的蛋白质属于LIR受体的B类亚家族，其包含两个或四个细胞外免疫球蛋白结构域，一个跨膜结构域和两个至四个基于细胞质免疫受体酪氨酸的抑制基序（ITIM）。 该受体在免疫细胞上表达，在那里与抗原呈递细胞上的MHC I类分子结合，并转导抑制免疫应答刺激的负信号。 人们认为控制炎症反应和细胞毒性有助于集中免疫反应并限制自身反应性。 已经为该基因发现了编码不同同工型的多个转录物变体。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。 |
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