p300 Monoclonal Antibody (RW105)
货号:MA1-16622
规格:100 µL
价格:5831
产品类型:标签抗体
品牌:Thermo Fisher
抗原:Fusion protein containing residues 1921-2023 of hu
物种:其它
宿主:小鼠
抗体亚型:IgG1, kappa
克隆号:RW105
荧光染料:其它
类型: | 一抗 | 同型对照: | |
浓度: | 1 mg/mL | 用法: | 1:50-1:200(ICC) ;1:50-1:200(IF);1:10-1:500(IP);1:250-1:500(WB) |
产品详细信息Suggested positive control: HeLa nuclear extract. 靶标信息EP300 encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. p300 is related by sequence to CPB (CREB-binding protein [CREB: cyclic-AMP responsive element binding protein]), and like CPB can stimulate transcription through activation of CREB. This EP300 activity is specifically inhibited by the adenovirus oncoprotein E1A. EP300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF.
数据: |
p300 Antibody (MA1-16622) in WB p300 detected in a HeLa nuclear extract using 1 (1:250). ECL: 20 minute exposure. |
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