Phospho-p300 (Ser1834) Polyclonal Antibody

货号：PA5-64531

规格：100 µL

价格：5956

产品类型：标签抗体

品牌：Thermo Fisher

抗原：A synthesized peptide derived from human E1A-assoc

物种：人/小鼠/大鼠

宿主：兔

抗体亚型：IgG

荧光染料：其它

类型:	一抗	同型对照：
浓度：	1 mg/mL	用法：	1:1000(WB)

产品详细信息Phospho-p300 (Ser1834) Polyclonal Antibody detects endogenous levels of p300 only when phosphorylated at Ser1834. 靶标信息EP300 encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. p300 is related by sequence to CPB (CREB-binding protein [CREB: cyclic-AMP responsive element binding protein]), and like CPB can stimulate transcription through activation of CREB. This EP300 activity is specifically inhibited by the adenovirus oncoprotein E1A. EP300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF.

数据：

Phospho-p300 (Ser1834) Antibody (PA5-64531) in WB Western blot analysis of p300 in PMA treated HeLa whole cell lysates using a Phospho-p300 (Ser1834) Polyclonal Antibody (Product # PA5-64531).

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