NSD2 Monoclonal Antibody (CL1063)
货号:MA5-24621
规格:100 µL
价格:5548
产品类型:标签抗体
品牌:Thermo Fisher
抗原:Recombinant protein corresponding to Human NSD2
物种:人
宿主:小鼠
抗体亚型:IgG2b, kappa
克隆号:CL1063
荧光染料:其它
类型: | 一抗 | 同型对照: | |
浓度: | 1 mg/mL | 用法: | 2-10 µg/mL(ICC) ;2-10 µg/mL(IF);1:500-1:1,000(IHC);1:500-1:1,000(WB) |
产品详细信息Immunogen sequence: SANGKTPSCE VNRECSVFLS KAQLSSSLQE GVMQKFNGHD ALPFIPADKL KDLTSRVFNG EPGAHDAKLR FESQEMKGIG TPPNTTPIKN GSPEIKLKIT KTYMNGKPLF ESSICGDHighest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 91%.Binds to an epitope located within the peptide sequence ALPFIPADKL as determined by overlapping synthetic peptides. 靶标信息This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4;14)(p16.3;q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences.
数据: |
NSD2 Antibody (MA5-24621) in ICCImmunocytochemistry-Immunofluorescence analysis of NSD2 in U-251 cells using NSD2 Monoclonal Antibody (CL1063) (Product # MA5-24621), showing specific staining in the nucleoplasm in green. Microtubule- and nuclear probes are visualized in red and blue, respectively (where available)NSD2 Antibody (MA5-24621) in IHC Immunohistochemical staining of NSD2 in human duodenum tissue shows strong nuclear immunoreactivity in glandular cells. Samples were probed using a NSD2 Monoclonal Antibody (Product # MA5-24621). |
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