Monkey CD14 ELISA Kit/猴CD14 ELISA试剂盒
货号：EP21RB,EP21RBX5,EP21RBX10
规格：96 Tests,5X96 Tests,10X96 tests
价格：6641,29884,57271
产品类型：Platinum ELISA
品牌：Thermo Fisher
物种：非人灵长类动物
宿主：其它
抗体亚型：其它
荧光染料：其它
灵敏度 | 0.2 ng/mL |
| 检测范围 | 0.205-50 ng/mL |
样本类型/体积 | 血清 50 μL 血浆 50 μL 上清液 50 μL |
操作时间 | 1 hr 20 min |
测试时间 | 4 hr 45 min |
Homogenous (no wash) | No |
| 批间变异系数（CV） | <12% |
| 批内变异系数（CV） | <10% |
仪器设备 | Colorimetric Microplate Reader 酶标仪 |
规格 | 5 x 96 Tests |
组份 | - 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖 |
储存温度 | 2-8℃ |
| Protein name | CD14 |
物种（Tested） | 非人类灵长类动物 |
试剂盒类型 | Sandwich ELISA Kit |
标记（染料） | HRP |
| 检测抗体偶联物 | Biotin |
| Monkey CD14 quantitates monkey CD14 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant monkey CD14.猴CD14定量检测血清，血浆，上清液中的猴CD14。该检测试剂盒将只识别天然和重组猴CD14。Target information 靶标信息CD14 is a 55 kDa GPI-anchored glycoprotein that is constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils. CD14 also serves as a multifunctional lipopolysaccharide receptor, and is released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 can discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. Further, CD14 has been shown to bind apoptotic cells, and can affect allergic, inflammatory and infectious processes. Alternative splicing results in multiple transcript variants encoding the same CD14 isoform. Diseases associated with CD14 dysfunction include mycobacterium chelonae infection and Croup.CD14是55 kDa GPI锚定的糖蛋白，在成熟的单核细胞，巨噬细胞和嗜中性粒细胞的表面组成性表达。 CD14还用作多功能脂多糖受体，并以分泌和酶切的GPI锚定形式释放到血清中。 CD14在急性期血清蛋白脂多糖结合蛋白（LBP）催化的反应中与脂多糖分子结合。可溶性sCD14可以区分脂多糖之间的微小结构差异，对于重组脂蛋白颗粒中和血清异源脂多糖很重要。此外，已经证明CD14结合凋亡细胞，并且可以影响变应性，炎性和感染性过程。选择性剪接导致编码相同CD14同种型的多个转录变体。与CD14功能障碍相关的疾病包括分枝杆菌分支杆菌感染和克劳普病。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。 |
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