Mouse DLL4 ELISA Kit/小鼠DLL4 ELISA试剂盒
货号：EM21RB,EM21RBX5,EM21RBX10
规格：96 Tests,5X96 Tests,10X96 tests
价格：6327,28472,54564
产品类型：Platinum ELISA
品牌：Thermo Fisher
物种：小鼠
宿主：其它
抗体亚型：其它
荧光染料：其它
灵敏度 | 0.2 ng/mL |
| 检测范围 | 0.2-50 ng/mL |
样本类型/体积 | 血清 50 μL 血浆 50 μL 上清液 50 μL |
操作时间 | 1 hr 20 min |
测试时间 | 4 hr 45 min |
Homogenous (no wash) | No |
| 批间变异系数（CV） | <12% |
| 批内变异系数（CV） | <10% |
仪器设备 | Colorimetric Microplate Reader 酶标仪 |
规格 | 5 x 96 Tests |
组份 | - 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖 |
储存温度 | 2-8℃ |
| Protein name | DLL4 |
| Protein aliases | Delta-like protein 4, Delta4, Drosophila Delta homolog 4 |
物种（Tested） | 小鼠 |
试剂盒类型 | Sandwich ELISA Kit |
标记（染料） | HRP |
| 检测抗体偶联物 | Biotin |
| Gene aliases | Delta4, Dll4 |
| Gene ID | (Mouse) 54485 |
| Gene symbol | Dll4 |
| UniProt ID | (Mouse) Q9JI71 |
| Mouse DLL4 quantitates mouse DLL4 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant mouse DLL4.小鼠DLL4定量分析血清，血浆，上清液中的小鼠DLL4。 该检测试剂盒将专门识别天然和重组小鼠DLL4。Target information 靶标信息Delta-like ligand 4 (DLL4), also know as Delta-4, is a homologue of the Drosophila delta protein, and functions as a transmembrane bound ligand to the notch receptor Notch1. DLL4 is expressed in the vasculature and plays a critical role in vascular development. It is induced by vascular endothelial growth factor (VEGF), as a negative feedback regulator to regulate angiogenic sprouting and promote the formulation of a differentiated vascular network. DLL4 has been found to be strongly expressed in tumor vessels of clear-cell renal tumors and bladder cancer, and inhibition of DLL4 results in increased vascular proliferation but defective maturation. This in turn leads to a decrease in tumor growth, with no apparent toxicity.Delta样配体4（DLL4），也称为Delta-4，是果蝇delta蛋白的同源物，并作为缺口受体Notch1的跨膜结合配体。 DLL4在脉管系统中表达，并在血管发育中起关键作用。 它是由血管内皮生长因子（VEGF）诱导的，它是负反馈调节剂，可调节血管生成的萌芽并促进分化血管网络的形成。 已经发现DLL4在透明细胞肾肿瘤和膀胱癌的肿瘤血管中强烈表达，并且对DLL4的抑制导致血管增殖增加但成熟不良。 反过来，这导致肿瘤生长减少，没有明显的毒性。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。 |
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