| 产品介绍 | | |
| Mouse anti Human CD61 antibody, clone Y2/51recognizes CD61, a ~105 kDa glycoprotein, also known as integrin beta 3 chain. This molecule associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) at the cell surface. CD61 is expressed on platelets and megakaryocytes in association with CD41, and on endothelial cells, monocytes, platelets and osteoclasts in association with CD51.CD61 is a receptor for fibrinogen, fibronectin, vWF, vitronectin and thrombospondin. |
| 产品详情 | | |
| Target Species | Human |
| Product Form | Purified IgG conjugated to R. Phycoerythrin (RPE) - lyophilized |
| Preparation | Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant |
| Fusion Partners | Spleen cells from immunised Balb/c mice were fused with cells of the NS1 myeloma cell line. |
| Buffer Solution | Phosphate buffered saline |
| Immunogen | Mouse TREM-1 Fc fusion protein. |
| Reconstitution | Reconstitute with 1.0ml distilled water |
| Preservative Stabilisers | 0.09%Sodium Azide1%Bovine Serum Albumin |
| Max Ex/Em | Fluorophore | Excitation Max (nm) | Emission Max (nm) |
| RPE 488nm laser | 496 | 578 |
| Regulatory | For research purposes only |
| Guarantee | 12 months from date of despatch |
| 存储条件 | | |
| Store at +4℃. DO NOT FREEZE.This product should be stored undiluted. Storage in frost-free freezers is not recommended. This product is photosensitive and should be protected from light.Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| 应用 | | |
| Application Name | Verified | Min Dilution | Max Dilution |
| Flow Cytometry | √ | Neat | |
| This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. |
| 文献 |
| 1.Phillips, D.R.et al.(1991) GPIIb-IIIa: the responsive integrin.Cell. 65 (3): 359-62.2.Hynes, R.O. (1992) Integrins: versatilit, modulation, and signaling in cell adhesion.Cell. 69 (1): 11-25.3.Michelson, A. D.et al. (1995) A panel of platelet mAb for the study of haemostasis and thrombosis in baboons.Leucocyte Typing V. Oxford University Press p 1230-1.4.Gatter, K.C.et al.(1988) The immunohistological detection of platelets, megakaryocytes and thrombi in routinely processed specimens.Histopathology. 13 (3): 257-67. |
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