CD79b Monoclonal Antibody (CB3-1), PE,

货号：12-0793-42

规格：100 Tests

价格：2167

产品类型：流式抗体

品牌：eBioscience

抗原：CD79b

物种：人

宿主：小鼠

抗体亚型：IgG

克隆号：CB3-1

荧光染料：PE

类型:	单抗	同型对照：	Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), PE
浓度：	5 µL/Test	用法：	5 µL (0.5 µg)/test(Flow)

产品详细信息Description: This CB3-1 monoclonal antibody reacts with human CD79b, the B cell antigen receptor Ig-beta chain. Together with the Ig alpha chain, also known as CD79a, this cell surface molecule forms a heterodimeric complex that associates with membrane immunoglobulin (mIgM). CD79b expression is exclusive to B lymphocytes and B cell lymphomas. Depending on the maturation state of the B cell, CD79b can be expressed either in the cytoplasm or on the cell surface. The CD79 receptor complex triggersnumerous signaling pathways to mediate B cell development, maintenance, and activation.Applications Reported: This CB3-1 antibody has been reported for use in flow cytometric analysis.Applications Tested: This CB3-1 antibody has been pre-titrated and tested by flow cytometric analysis of normal peripheral blood cells. This can be used at 5 µL (0.5 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.Filtration: 0.2 µm post-manufacturing filtered.靶标信息CD79b is the B cell antigen receptor Ig beta chain (BCR-Ig beta), which associates with B cell antigen receptor Ig alpha chain to form a functional heterodimer that interacts with membrane immunoglobulin (mIg). The mIgM component binds antigen and the Ig alpha /I g beta heterodimer tranduces signals.

数据

CD79b Antibody (12-0793-42) in FlowStaining of normal human peripheral blood cells with Anti-Human CD19 APC (Product # 17-0199-42) and Mouse IgG1 K Isotype Control PE (Product # 12-4714-81) (left) or Anti-Human CD79b PE (right). Cells in the lymphocyte gate were used for analysis.

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参考文献

1. PloS oneSpontaneous production of immunoglobulin M in human epithelial cancer cells.

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