| 产品介绍 | | |
| Goat anti Human TRAF2 antibodyrecognizes human tumor necrosis factor (TNF) receptor associated factor 2 (TRAF2), a member of the TNF receptor associated factor (TRAF) protein family. TRAF2 is an adapter protein and signal transducer, which acts downstream of the TNF receptor. TRAF2 directly binds with TNF receptors and other TRAF proteins, and is essential for TNF alpha mediated activation of MAPK8/JNK and NF-kappaB. TRAF2 plays a role in apoptosis, through the formation of a heterodimeric complex with TRAF1, and interaction with the IAP family members cIAP1 and cIAP2, functioning as a mediator of the anti-apoptotic signals from TNF receptors.Goat anti Human TRAF2 recognizes TRAF2 as a band of 46 kDa in a range of human cell line lysates. Cross reactivity with rodent cell lines is also observed. |
| 产品详情 | | |
| Target Species | Human |
| Product Form | Purified IgG - liquid |
| Preparation | Goat polyclonal antibody purified by affinity chromatography. |
| Buffer Solution | TRIS buffered saline. |
| Preservative Stabilisers | 0.02% Sodium Azide (NaN3)0.5% Bovine Serum Albumin |
| Immunogen | Synthetic peptide sequence C-KMEAKNSYVRDD from the C-terminal region of TRAF2. |
| Acknowledgements | PrecisionAb is a trademark of Bio-Rad Laboratories. |
| Regulatory | For research purposes only |
| Guarantee | 12 months from date of despatch |
| 存储条件 | | |
| Store undiluted at -20°C, avoiding repeated freeze thaw cycles |
| 应用 | | |
| Application Name | Verified | Min Dilution | Max Dilution |
| Western Blotting | √ | | |
| This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. |
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