Mouse anti Human AMH, clone 5/6
货号:MCA2246T,MCA2246
规格:0.1 ml,1 ml
价格:1343,8075
产品类型:免疫组化一抗
品牌:Bio-Rad
抗原:AMH
物种:人
宿主:小鼠
抗体亚型:IgG1
克隆号:5/6
荧光染料:Purified
产品介绍 | | |
Mouse anti Human AMH, clone 5/6recognizes human anti-mullerian hormone (AMH), originally classified as a foetal testicular hormone that inhibits Mullerian duct development. AMH is expressed post-natally by immature Sertoli cells, and to a lesser degree by granulosa cells. AMH plays a role in testicular differentiation and in the regulation of ovarian follicle growth.AMH is a member of the TGF beta superfamily. It is secreted as a homodimeric ~140 kDa disulphide linked precursor that is cleaved to release the mature ~30 kDa homodimer. |
产品详情 | | |
Target Species | Human |
Product Form | Concentrated Tissue Culture Supernatant - liquid |
Fusion Partners | Spleen cells from immunised T/O outbred mice were fused with cells of the SP2/0 myeloma cell line. |
Buffer Solution | Phosphate buffered saline |
Immunogen | Synthetic peptide derived from human AMH (VPTAYAGKLLISLSEERISAHHVPNMVATEC) |
Preservative Stabilisers | 0.01%Sodium Azide |
Regulatory | For research purposes only |
Guarantee | 12 months from date of despatch |
存储条件 | | |
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. |
应用 | | |
Application Name | Verified | Min Dilution | Max Dilution |
Flow Cytometry | √ | | |
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. |
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文献 |
1.Van Saen, D.et al.(2010) Meiotic activity in orthotopic xenografts derived from human postpubertal testicular tissue.Hum Reprod. 26: 282-93.2.Gruijters, M.Jet al.(2003) Anti-Müllerian hormone and its role in ovarian function.Mol Cell Endocrinol. 211 (1-2): 85-90.3.Weenen, C.et al. (2004) Anti-Mullerian hormone expression pattern in the human ovary: potential implications for initial and cyclic follicle recruitment.Mol Hum Reprod10: 77-83.4.Papanastasopoulos, P.et al.(2009) A case of complete androgen insensitivity syndrome presenting with incarcerated inguinal hernia: an immunohistochemical study.Fertil Steril. 92: 1169.e11-4. |
技术参数 产品应用 WB
产品类型 Monoclonal Antibody
推荐用于 WB
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