Mouse anti Human KIR antibody, clone NKVFS1
货号：MCA2243PE
规格：100 Tests
价格：3936
产品类型：流式抗体
品牌：Bio-Rad
抗原：KIR
物种：人
宿主：小鼠
抗体亚型：IgG1
克隆号：NKVFS1
荧光染料：PE
| 产品介绍 | | |
| Mouse anti Human KIR antibody, clone NKVFS1recognizes KIR2D members of the killer cell immunoglobulin (Ig)-like receptor (KIR) family, CD158a, CD158b and P50.3. KIR2D family members are cell surface glycoproteins with two Ig domains, which are expressed on natural killer cells and some T cells.Mouse anti Human KIR antibody, clone NKVFS1 recognizes the long and short forms CD158a and CD158b (KIR2DL, KIR2DS1 and KIR2DS2 respectively) and also p50.3 (KIR2DS4).Mouse anti Human KIR antibody, clone NKVFS1 is reported to have functional activity, activating NK cell cytotoxicity via KIR2DS and inhibiting via KIR2DL forms.. |
| 产品详情 | | |
| Target Species | Human |
| Product Form | Purified IgG conjugated to R. Phycoerythrin (RPE) - liquid |
| Reconstitution | Reconstitute with 1.0 ml distilled water |
| Preparation | Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant |
| Buffer Solution | Phosphate buffered saline |
| Preservative Stabilisers | 1% Bovine Serum Albumin |
| Max Ex/Em | Fluorophore | Excitation Max (nm) | Emission Max (nm) |
| RPE 488nm laser | 496 | 578 |
| Regulatory | For research purposes only |
| Guarantee | 12 months from date of despatch |
| 存储条件 | | |
| Prior to reconstitution store at +4℃. Following reconstitution store at +4℃.DO NOT FREEZE.This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use. |
| 应用 | | |
| Application Name | Verified | Min Dilution | Max Dilution |
| Flow Cytometry | √ | | |
| This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. |
| 推荐产品 |
| Description | Product Code | Applications | Pack Size |
| Rat IgG2a Negative Control:RPE | MCA1212PE | F | 100 Tests |
| 文献 |
| 1.Spaggiari, G.M.et al.(2002) Soluble HLA class I molecules induce natural killer cell apoptosis through the engagement of CD8: evidence for a negative regulation exerted by members of the inhibitory receptor superfamily.Blood. 99 (5): 1706-14.2.Spaggiari, G.M.et al.(2002) Soluble HLA class I induces NK cell apoptosis upon the engagement of killer-activating HLA class I receptors through FasL-Fas interaction.Blood. 100 (12): 4098-107.3.Older Aguilar, A.M.et al.(2010) Coevolution of killer cell Ig-like receptors with HLA-C to become the major variable regulators of human NK cells.J Immunol. 185 (7): 4238-51. |
技术参数 产品应用 Flow
产品类型 Monoclonal Antibody
推荐用于 Flow
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