| 产品介绍 | | |
| Rabbit anti Human MBP antibodyrecognizes human myelin basic protein (MBP), an abundant protein component of the myelin membrane and is reported to have a role in its formation and stabilisation. |
| 产品详情 | | |
Target Species | Human |
Product Form | Purified IgG - liquid |
Preparation | Purified IgG prepared by affinity chromatography on Protein G |
Buffer Solution | Phosphate buffered saline |
Preservative Stabilisers | 0.09% Sodium Azide (NaN3) |
Approx. Protein Concentrations | IgG concentration 1.0 mg/ml |
Immunogen | Native Myelin Basic Protein from Human brain. |
Regulatory | For research purposes only |
Guarantee | 12 months from date of despatch |
| 存储条件 | | |
| This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. |
| 应用 | | |
Application Name | Verified | Min Dilution | Max Dilution |
ELISA | √ | 1/100 | 1/400 |
Immunofluorescence | √ | | |
Western Blotting | √ | | |
| This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.Western Blotting0300-0082 detects band at 18.5 kDa on reducing SDS-PAGE against rat brain lysate. |
| 二抗相关产品 |
Description | Product Code | Applications | Pack Size |
Goat anti Rabbit IgG (Fc):Biotin | STAR121B | E;WB | 1 mg |
Goat anti Rabbit IgG (Fc):FITC | STAR121F | Flow | 1 mg |
Goat anti Rabbit IgG (Fc):HRP | STAR121P | E;WB | 1 mg |
Goat anti Rabbit IgG (H/L):HRP | STAR124P | C;E;WB | 1 mg |
Sheep anti Rabbit IgG:FITC | STAR34B | C;F | 1 mg |
| 数据 |
| Published customer image:Rabbit anti Human MBP antibody (0300-0082) used to evaluate MBP expression in mouse tissue lysates by western blotting.Image caption:Western blot analysis of myelin basic protein (MBP) and β-tubulin expression levels in whole cell lysates derived from the 6-months old Er1 F/+ and Er1Cx/- cortices, optical nerves (OP.N.), cerebella and hippocampi (as indicated). |
| 文献 |
| 1. Seiberlich, V.et al.(2015) Downregulation of the microtubule associated protein Tau impairs process outgrowth and myelin basic protein mRNA transport in oligodendrocytes.Glia. 63 (9): 1621-35.2. Krajnak, K.et al.(2016) Long-term daily vibration exposure alters current perception threshold (CPT) sensitivity and myelinated axons in a rat-tail model of vibration-induced injury.J Toxicol Environ Health A. 79 (3): 101-11.3. Garinis, G.et al.(2021) DNA damage in tissue-resident macrophages leads to age-related neurodegenerationRes Sq. Dec 01 [Epub ahead of print]. |
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