Applications

FA

Synonyms:

CHEMBL1257064, F0579-0037

Formulation:

Crystalline solid

Chemical Name:

N-(6-methyl-1,3-benzothiazol-2-yl)-2-[(4-oxo-3-phenyl-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)sulfanyl]acetamide

Molecular Formula:

C₂₂H₁₈N₄O₂S₃

Molecular Weight:

466.6

CAS Number

686770-61-6

Purity:

≥95%

Storage Conditions:

Product should be kept at -20°C.

References:

Chen, B., Dodge, M. E., Tang, W., Lu, J., Ma, Z., Fan, C. W., ... & Lum, L. (2009). Small molecule–mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer.Nature chemical biology,5(2), 100-107.

Loh, Y. N., Hedditch, E. L., Baker, L. A., Jary, E., Ward, R. L., & Ford, C. E. (2013). The Wnt signalling pathway is upregulated in an in vitro model of acquired tamoxifen resistant breast cancer.BMC cancer,13(1), 174.

Mo, M. L., Li, M. R., Chen, Z., Liu, X. W., Sheng, Q., & Zhou, H. M. (2013). Inhibition of the Wnt palmitoyltransferase porcupine suppresses cell growth and downregulates the Wnt/β-catenin pathway in gastric cancer.Oncology letters,5(5), 1719-1723.