Applications

FA

Synonyms:

Inhibitor of Wnt Production-4

Formulation:

Crystalline solid

Chemical Name:

N-(6-methyl-2-benzothiazolyl)-2-[[3,4,6,7-tetrahydro-3-(2-methoxyphenyl)-4-oxothieno[3,2-d]pyrimidin-2-yl]thio]-acetamide

Molecular Formula:

C₂₃H₂₀N₄O₃S₃

Molecular Weight:

496.6

CAS Number

686772-17-8

Purity:

≥95%

Storage Conditions:

Product should be kept at -20°C.

References:

Chen, B., Dodge, M. E., Tang, W., Lu, J., Ma, Z., Fan, C. W., ... & Lum, L. (2009). Small molecule–mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer.Nature chemical biology,5(2), 100-107.

Hudson, J., Titmarsh, D., Hidalgo, A., Wolvetang, E., & Cooper-White, J. (2011). Primitive cardiac cells from human embryonic stem cells.Stem cells and development,21(9), 1513-1523.

Bilir, B., Kucuk, O., & Moreno, C. S. (2013). Wnt signaling blockage inhibits cell proliferation and migration, and induces apoptosis in triple-negative breast cancer cells.J Transl Med,11(1), 280.