PDX1 Polyclonal Antibody
货号:PA5-84405
规格:100 µL
价格:6049
产品类型:免疫组化一抗
品牌:eBioscience
物种:人
宿主:兔
抗体亚型:IgG
荧光染料:Purified
类型: | 多抗 | 同型对照: | |
浓度: | 0.1 mg/mL | 用法: | 1-4 µg/mL(ICC);1-4 µg/mL (IF);1:20-1:50(IHC (P)) |
免疫原性: | Recombinant protein corresponding to Human PDX |
产品详细信息Immunogen sequence: DISPYEVPPL ADDPAVAHLH HHLPAQLALP HPPAGPFPEG AEPGVLEEPN RVQLPFPWMK STKA靶标信息pdx-1 (pancreas duodenum homeobox-1, also known as IPF-1, IDX-1, and STF-1) is a transcription factor that has been shown to activate insulin, glucokinase, IAPP, and somatostatin gene transcription. Significant interest surrounds this proteins glucose-dependent regulation of insulin gene transcription. Additionally, pdx-1 has been studied for its role in pancreatic development which includes maturation and differentiation of pancreatic precursor cells. Mutations in the pdx-1 gene have been shown to cause pancreatic agenesis, maturity-onset diabetes of the young, and type II diabetes.
数据 |
PDX1 Antibody (PA5-84405) in IF Immunofluorescent analysis of PDX1 in HeLa cells using a PDX1 polyclonal antibody (Product # PA5-84405). The analysis shows localization to nucleoplasm. PDX1 Antibody (PA5-84405) in IHC Immunohistochemical analysis of PDX1 in human duodenum and prostate tissues using a PDX1 polyclonal antibody (Product # PA5-84405). Corresponding RNA-seq data are presented for the same tissues. |
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二抗荧光二抗免疫组化一抗标签抗体 |
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