| 产品介绍 | | |
| Mouse anti Pig CD31 antibody, clone LCI-9recognizes porcine Platelet endothelial cell adhesion molecule, also known as CD31 or PECAM-1. Porcine CD31 is a 740 amino acid ~140 kDa single pass type 1 transmembrane glycoprotein bearing sixIg-like C2-typedomains. CD31 is expressed by various cell types, but particularly by endothelial cells where it is required for leukocyte transendothelial migration (UniProt:Q95242).Mouse anti Pig CD31 antibody, clone LCI-9 has been used successfully for recognition of porcine CD31 by flow cytometry (Petersonet al.2005) and immunofluorescence microscopy (Nasuet al.1999). |
| 产品详情 | | |
| Target Species | Pig |
| Product Form | Tissue Culture Supernatant - liquid |
| Preservative Stabilisers | 0.09% Sodium Azide (NaN3) |
| Immunogen | Porcine CD31/human IgGFc fusion protein. |
| Regulatory | For research purposes only |
| Guarantee | 12 months from date of despatch |
| 存储条件 | | |
| This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. |
| 应用 | | |
| Application Name | Verified | Min Dilution | Max Dilution |
| Flow Cytometry | √ | | |
| This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. |
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| 文献 |
| 1.J Immunol. 174 (12): 8072-81.Nasu, K.et al.(1999) Alpha-galactosyl-mediated activation of porcine endothelial cells: studies on CD31 and VE-cadherin in adhesion and signaling.Transplantation. 1999 Sep 27;68(6): 861-7.2.Peterson, M.D.et al.(2005) Monocyte-induced endothelial calcium signaling mediates early xenogeneic endothelial activation.Am J Transplant. 5: 237-47.3.Harrower, T.P.et al.(2006) Long-term survival and integration of porcine expanded neural precursor cell grafts in a rat model of Parkinson's disease.Exp Neurol. 197: 56-69.4.Al-Shalmani, S.et al.(2011) Quercetin and its principal metabolites, but not myricetin, oppose lipopolysaccharide-induced hyporesponsiveness of the porcine isolated coronary artery.Br J Pharmacol. 162: 1485-97. |
QQ:1749072012