Rabbit anti Rat NMDA receptor NR2B (pTyr1472) antibody
货号：AHP1004
规格：0.1 ml
价格：4063
产品类型：免疫组化一抗
品牌：Bio-Rad
抗原：NMDA receptor NR2B (pTyr1472)
物种：大鼠
宿主：兔
抗体亚型：IgG
荧光染料：Purified
| 产品介绍 | | |
| Rabbit anti Rat NMDA receptor NR2B (pTyr1472) antibodyrecognizes NMDA receptor NR2B, also known as glutamate receptor ionotropic, NMDA 2B (GluN2B), glutamate [NMDA] receptor subunit epsilon-2 and N-methyl D-aspartate receptor subtype 2B (NMDAR2B), when phosphorylated at tyrosine 1472.Receptors for NMDA belong to a group of ionotropic glutamate receptors which play a key role in the mediation of glutamate neurotransmission within the mammalian central nervous system (CNS), including involvement in memory and learning processes. Several antagonists and agonists of NMDA receptors (NMDAR) have been identified, including the glutamate analogue Homoquinolinic acid, which displays a higher affinity for NR2B-containing NMDAR. Properties of NMDAR include modulation by glycine, inhibition by Zn2+, voltage-dependent Mg2+blockade and high Ca2+permeability.The involvement of NMDAR in the CNS has become a focus area for neurodegenerative diseases such as Alzheimer’s disease (Popkeet al.2003) and also epilepsy and ischemic neuronal cell death. |
| 产品详情 | | |
| Target Species | Rat |
| Product Form | Purified IgG - liquid |
| Antiserum Preparation | Antisera to NMDA receptor NR2B subunit were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography. |
| Buffer Solution | 10mM HEPES pH7.5. |
| Preservative Stabilisers | 0.09% Sodium Azide0.01% Bovine Serum Albumin50% Glycerol |
| Immunogen | A synthetic phosphopeptide corresponding to an amino acid sequence within the NR2B subunit of the NMDA receptor, which includes phosphorylated Tyr1472. |
| Regulatory | For research purposes only |
| Guarantee | 12 months from date of despatch |
| 存储条件 | | |
| This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. |
| 应用 | | |
| Application Name | Verified | Min Dilution | Max Dilution |
| Western Blotting | √ | | 1/1000 |
| This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. |
| 二抗 |
| Description | Product Code | Applications | Pack Size |
| Goat anti Rabbit IgG (Fc):Biotin | STAR121B | E,WB | 1mg |
| Goat anti Rabbit IgG (H/L):HRP | STAR124P | C,E,WB | 1mg |
技术参数 产品应用 wb
产品类型 Polyclonal Antibody
推荐用于 wb
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