Cytochrome C Monoclonal Antibody (6H2.B4), Alexa Fluor 555
货号:MA3-38200-A555
规格:50 µl
价格:4070
产品类型:流式抗体
品牌:Thermo Fisher
物种:人/小鼠/大鼠
宿主:小鼠
抗体亚型:其它
荧光染料:Alexa Fluor 555
类型: | 单抗 | 同型对照: | IgG1, kappa |
免疫原性: | Rat Cytochrome C. | 用法: | 1-10 µg/mL(IF) |
Product Specific InformationThis antibody reacts with native Cytochrome C, but does not recognize denatured cytochrome C. The antibody recognizes a region in the vicinity of amino acid 62 of rat Cytochrome C.Target InformationCytochrome C is an electron transporting protein that resides within the intermembrane space of the mitochondria, where it plays a critical role in oxidative phosphorylation and the production of cellular ATP. Release of cytochrome C from the mitochondria to the cytosol is triggered by apoptotic stimuli. In the cytoplasm, the cytochrome C binds apoptotic protease activating factor which activates the apoptotic initiator procaspase 9. Cytosolic cytochrome C functions in the activation of caspase 3, an ICE family molecule that is a key effector of apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.