Mouse IgM Isotype Control/小鼠IgM同型对照
货号：02-6800
规格：1 mg
价格：2505
产品类型：小鼠同型对照
品牌：Thermo Fisher
抗原：Mouse IgM
物种：其它
宿主：小鼠
抗体亚型：IgM
荧光染料：其它
| 类型: | | 同型对照： | |
| 浓度： | 1 mg/mL | 用法： | Assay-Dependent(对照试剂（Ctrl)); Assay-Dependent (ELISA) |
| 产品详细信息This antibody will react with sheep red blood cells, but is suitable as a negative reagent control for most applications. 靶标信息IgM (Immunoglobulin M) is expressed intracellularly during the early stages of B lymphopoiesis, and then on the surface of more mature B cells in the bone marrow and peripheral B cells. The isotype of a primary antibody and its application can result in background staining. Primary antibody background noise can be caused by binding to Fc receptors on target cells; by non-specific interactions with cellular proteins, carbohydrates, and lipids; or by cell autofluorescence. Isotype control antibodies can act as negative controls to help differentiate non-specific background signal from specific antibody signal because they have no relevant specificity to a target antigen. While isotype controls are most commonly used in flow cytometry, they are also useful in other applications such as chromatin immunoprecipitation (ChIP), immunohistochemistry, and gel shifts. Isotype controls should match with the primary antibody species and isotype so that the level of specific staining by the primary antibody may be accurately determined. If using directly labeled primary antibodies, the isotype control works best if conjugated with the same label as the test antibody. |
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| 参考文献： |
1.Journal of immunology (Baltimore, Md. : 1950) IL-4-producing CD8+ T cell clones can provide B cell help. |
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